P-147: Ovarian Function over Time in Adult Rats after Tubal Sterilization

Background: Tubal sterilizatio (TS) is a widely applied contraceptive method worldwide. Although most studies have described sterilization as a safe method, there are reports of TS complications. The aim of this study was to evaluate the effects of TS on ovarian function. Materials and Methods: The study comprised of 2 protocols A and B. A Protocol: survey ovarian hormone and B protocol: study of estrous cycle. Each of the protocols included control, sham and TS (Pomeroy) groups. In protocol A, rats serum estradiol was measured 15, 45 days 3 and 6 months after intervention. In protocol B, on days 15 and 45 and months 3 and 6 after the intervention, animal’s estrous cycle was followed for 15 days. Results: Our results showed that serum estradiol significantly decreased in rats undergone TS (p<0.05). Also TS caused irregularity in estrous cycle after 15, 45 days, 3 months, and 6 months. Conclusion: TS decreased estradiol of serum. Complications of TS may be due to decreased ovarian function.